Repository series · ncbi-prjna211641
Expression data from endothelial cells sorted from breast cancer cells MDA-MB231 as compared with normal endothelial cells
We studied the crosstalk between tumor and endothelial cells to explore the role of tumor microenvironment on cancer growth and progression. As part of our investigation, we showed that contact-dependent interaction of endothelial cells with breast tumor cells triggered the differential expression of a large number of genes in endothelium. Overall design: Endothelial and MDA-MB231 cells were co-cultured together under serum- cytokine-free environment for 5 days followed by sorting endothelial cells and extracting RNA for microarray analysis. All conditions were made in triplicate. Endothelial cells were obtained using the methods described in Seandel M. & Butler J.M., 2008. WCMC-Q Genomics Core
The accession and its GCC connection are verified. Registration alone does not establish that the broader research programme remains active.
01 / Project overview
What the record establishes.
- Geographic scope
- Qatar connection indexed in BioProject metadata
- Project type
- Repository project
- Research domain
- Human health and population genomics
- Years
- 2013–
- Lifecycle status
- repository_recorded
- Status basis
- Registered in NCBI BioProject on 2013/07/11; operational lifecycle is not asserted.
- Status evidence date
- 2013-07-11
- Scale
- 1 BioProject accession grouped by matching submitter, date, data type and narrative.
02 / Organizations and population
Who and what the project connects.
- Lead organizations
- Weill Cornell Mecial College - Qatar
- Partner organizations
- Not stated
- Organism / population
- Homo sapiens
03 / Data and access
What exists and how it can be reached.
Data types
- Transcriptome or Gene expression
- Array
- Transcriptome
Data access
Public repository metadata with linked data where supplied by the submitter
Identifiers
- BioProject
PRJNA211641
04 / Evidence and provenance
Why the record is included.
Inclusion basis
Exact country-name match in authoritative NCBI BioProject metadata; repeated submissions are grouped into one Atlas series.
Editorial note
Repository verification confirms the accession and regional connection, not whether the broader research programme remains active.
Sources
- primary record source Verified 2026-08-15
Release v0.2.0